Apex Medical Device Design LLC
R&D based Cosmeceutical Company
Apex is developing Curly Hair-on-Chip, a novel DNA curly hair typing kit that will support individualized hair-relaxing treatment.
We are creating The Collaborative AI Black Hair Typing Project, collaborating with philanthropists, angel investors & contract research organizations (CROs)
You are welcomed to join us in this endeavor!
Curly Hair-on-Chip
Building Science-Based Inventions by Vertical Research Model
Apex Medical is a cosmeceutical, pre-seed, women owned startup company founded by curiosity-driven Dr. Nedaa Al Jasim, a medical doctor with 40+ years of experience.
Apex advances the biology of curly and coily hair follicle using a ”vertical “ research strategy; wherein a solo inventor built a series of scientific inventions, one milestone on top of the other.
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We invented CurlRelaxTM, the first-in-class ingestible herbal hair follicle relaxing treatment, patent pending in the USA and internationally;
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Dr. Al Jasim published her 1st hypothesis: Curly hair is sculpted by hyperactive Arrector Pili muscle;
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Dr. Al Jasim published her 2nd hypothesis: Wnt gene-secreting cells orchestrate hair types;
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The latest invention under development, patent-pending, is Curly Hair-on-Chip, DNA test kit.
We aspire to make millions of people look at their best
First: The hyperactive contracted Arrector Pili muscle curve the follicle
The muscle generate mechanical force that curve the follicle
We invented the first-in-class ingestible curly hair relaxing treatment that get to the root cause of curling.
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CurlRelax is derived from a safe medicinal herb to give women and men a desired, healthy, easily manageable relaxed hair; simplify the daily haircare rituals and reduce cost. The question is how CurlRelax works? It is known that curly hair shaft is designed by a curved hair follicle, but why does the follicle curve?
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We propose that follicle curling is the result of a contracted “hyperactive” Arrector Pili muscle of the follicle. This is science-based hypothesis! By relaxing this muscle, we promote the growth of a relaxed healthy hair, and avoid chemical side effects, both local and systemic. CurlRelax can also prevent tension alopecia (hair fall) caused by tight breads and logs.
The Arrector Pili hypothesis received recognition from medical journals and social media
The hypothesis title: Curly HF is sculpted by a contracted arrector pili muscle: a hypothesis with treatment implication.
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Was published by the American Journal of Pharmacology and Pharmacotherapeutics (October 28, 2024). doi: 10.36648/2393-8862.11.S1.01
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The story of CurlRelax appeaedr on the cover page of The USA Leaders Building America, special issue: Innovative Women in Biotech Leading the Future of Healthcare Industry: “Dr Nedaa Al Jasim is revolutionizing curly hair care with science and ingenuity.”
CurlRelax Product: a product by process patent
Herbal oil nanoemulsification process
What is Our Secret Sauce?
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Apex invented a process to produce the uni-sourced herbal emulsion formulation of HairRelax.
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Our 3-steps manufacturing process is characterized by:
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One selected herb as a source of all the required ingredients, i.e., one-for-all;
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One green solvent is added to the water phase; and
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Unique extraction kinetics, wherein the oil is extracted drop-by-drop and is simultaneously emulsified.
Patent-pending product in
the USA and Internationally
CurlRelax product is under development.
Second: The 2nd hypothesis is Wnt gene-secreting cells orchestrate curly hair type
Novel genetic, molecular and cellular crosstalk in the peri-follicular space
hypothesis title: Curly hair from genes (GWAS) to functional genomics: Wnt-secreting and –receiving macrophages orchestrate hair types: a hypothesis with functional implications. Posted on preprint platform in December16,2024.
https://www.preprints.org/manuscript/202412.1222/v1
This molecular gene-receptor interactions need proof-of-concept artificial intelligence (AI) study.
The name of the projects, The Black “Functional Genomic” AI Lab, relates to the above hypothesis. We were invited to republish it in prestigious peer reviewed journals. But, we plan to do so after the CurlRelaxTM AI lab is created.
Third: Decade-long efforts comes to fruition!
Apex project curly Hair-on Chip science is at the intersection of pharmacology mechanism of action (MOA), genetics, aesthetic medicine and immunology.
Apex hypothesis is setting the stage for a new era in understanding when, what, and how the micro-environment controls the gene expression of human curly and coily hair. We are writing a new chapter in human biology and genetics.
This functional genomic mechanism that need AI proof-of-concept study/
Curly Hair-on-Chip DNA Kit
The Collaborative AI Black Hair Typing Project
Finally, setting the stage for a new era in curly hair follicle research and individualized product development.
Better Together!
Philanthropist and Angel Investors are welcomed
to join us in this endeavor
Together, we will develop and commercialize Apex innovative patent-pending
Curly Hair-on-Chip DNA Kit
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individualized treatment
&
Trailblaze the curly haircare market
